What is Nattokinase?

2024-03-07 11:22:19

What is Nattokinase?

Nattokinase is an chemical determined from the Japanese matured soybean dish called "natto." It is delivered by the bacterium Bacillus subtilis amid the maturation prepare of soybeans to form natto, a conventional Japanese nourishment known for its special surface, flavor, and well-being benefits. Nattokinase has picked up consideration for its potential health-promoting properties, especially its capacity to back cardiovascular health.

Protein Action: Nattokinase may be a protease protein, which implies it has proteolytic (protein-digesting) action. It is mindful for the fibrinolytic (clot-dissolving) properties watched in natto.

Fibrinolytic Activity: Nattokinase has been appeared to have strong fibrinolytic action, meaning it can break down fibrin, a protein included in blood clot arrangement. By advancing fibrinolysis, nattokinase may offer assistance to preserve sound blood stream and circulation.

Cardiovascular Health: Due to its fibrinolytic movement, nattokinase is frequently advanced for its potential cardiovascular benefits. A few considers propose that nattokinase supplementation may offer assistance back solid blood weight levels, make strides blood vessel work, and diminish the hazard of blood clots and cardiovascular events.

Anti-Inflammatory Properties: Nattokinase has moreover been examined for its potential anti-inflammatory impacts. By decreasing aggravation in blood vessels and tissues, nattokinase may contribute to in general cardiovascular wellbeing and decrease the hazard of inflammatory-related conditions.

Other Potential Benefits: In addition to its cardiovascular effects, nattokinase has been investigated for its potential benefits in other areas, such as promoting healthy digestion, supporting immune function, and enhancing overall wellness. However, more research is needed to fully understand these potential effects.

Safety and Side Effects: Nattokinase is generally considered safe for most people when consumed in moderate amounts as part of the diet or as a dietary supplement. However, as with any supplement, some individuals may experience side effects or interactions, particularly if they have certain medical conditions or are taking medications. It's important to consult with a healthcare professional before starting nattokinase supplementation, especially if you have any pre-existing health conditions or concerns.

What is Nattokinase used for?

Nattokinase is a natural enzyme that is derived from fermented soybeans, specifically from a traditional Japanese dish called natto. It has been used for centuries in Japanese culture as a folk remedy for promoting heart health. Nattokinase is believed to have fibrinolytic properties, meaning it helps to break down and dissolve blood clots in the body. As a result, it is commonly taken as a dietary supplement to support cardiovascular health and maintain healthy blood circulation.

Is Nattokinase safe?

Nattokinase is generally considered safe for most people when taken in appropriate doses. However, it may interact with certain medications and increase the risk of bleeding. Therefore, it is important to consult with a healthcare professional before starting any new supplement, especially if you have a bleeding disorder, are taking anticoagulant medications, or have upcoming surgery. Additionally, pregnant and breastfeeding women should avoid using nattokinase, as there is insufficient evidence regarding its safety during these periods.Nattokinase is generally considered safe for most people when consumed in moderate amounts as part of the diet or as a dietary supplement. However, as with any supplement, it's important to use caution and follow recommended guidelines to minimize the risk of adverse effects.

Side Effects: Nattokinase is a natural enzyme derived from natto, a fermented soybean dish. When taken as a dietary supplement, some individuals may experience mild side effects such as digestive discomfort, nausea, diarrhea, or allergic reactions. These side effects are usually rare and mild, but if they occur, it's advisable to discontinue use and consult with a healthcare professional.

Blood Thinning Effects: Nattokinase has fibrinolytic activity, meaning it can help dissolve blood clots by breaking down fibrin, a protein involved in clot formation. While this property may be beneficial for cardiovascular health, it also means that nattokinase has blood-thinning effects. Individuals who are already taking anticoagulant or antiplatelet medications (blood thinners) should use caution when taking nattokinase, as it may increase the risk of bleeding or interact with their medications. It's important to consult with a healthcare professional before starting nattokinase supplementation, especially if you are taking any medications or have underlying health conditions.

Pregnancy and Breastfeeding: There is limited research on the safety of nattokinase supplementation during pregnancy and breastfeeding. As a precaution, pregnant or breastfeeding women should avoid nattokinase supplements unless recommended by a healthcare professional.

Allergies and Sensitivities: Individuals with soy allergies or sensitivities should use caution when consuming nattokinase, as it is derived from fermented soybeans. While nattokinase supplements typically contain purified forms of the enzyme, there is still a risk of allergic reactions in sensitive individuals. It's important to read product labels carefully and consult with a healthcare professional if you have known allergies or sensitivities to soy.

Quality and Purity: When choosing a nattokinase supplement, it's important to select a reputable brand that undergoes rigorous testing for quality, purity, and potency. Look for products that are manufactured by reputable companies, adhere to Good Manufacturing Practices (GMP), and have undergone third-party testing for quality and purity.

How fast does Nattokinase work?

The speed at which nattokinase works can vary depending on various factors, such as the individual's overall health, the dosage taken, and the specific condition being targeted. Some people may experience noticeable benefits within a few days, while others may require several weeks of consistent use to notice any changes. It is important to remember that nattokinase is not a quick fix and should be used as part of a long-term health regimen for optimal results.

Overall, nattokinase is a natural enzyme derived from natto that has gained popularity for its potential cardiovascular and health-promoting effects. While more research is needed to confirm its benefits and mechanisms of action, nattokinase remains an interesting area of study in the field of nutritional and functional medicine.

If you have further questions or would like to learn more about nattokinase, please feel free to contact us via email at sales@pioneerbiotech.com. We are always here to assist you!


1. Sumi H, et al. A unique strong fibrinolytic enzyme (nattokinase) in the vegetable cheese natto; a typical and popular soybean food in the Japanese diet.

2. Maruyama M, et al. Fibrinolytic and anticoagulant activities of highly purified nattokinase from Bacillus subtilis.

3. Fujita M, et al. Nattokinase, a fibrinolytic enzyme derived from Bacillus subtilis, inhibits human prolyl hydroxylase.

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