What does Nattokinase do?

2024-03-07 11:22:46

What does Nattokinase do?

Promotes Fibrinolysis: Fibrin may be a protein that shapes a mesh-like structure to assist with blood clotting and wound mending. In any case, over the top or unusual clot arrangement can lead to wellbeing issues such as thrombosis, stroke, or heart attack. Nattokinase makes a difference to break down fibrin, advancing fibrinolysis and avoiding the arrangement of intemperate blood clots.

Nattokinase is an protein inferred from the Japanese aged soybean dish called natto. This chemical is known for its fibrinolytic action, which implies it has the capacity to break down fibrin, a protein included in blood clot formation.

Improves Blood Flow: By breaking down fibrin, nattokinase makes a difference to preserve solid blood stream and circulation all through the body. This may offer assistance anticipate blockages in blood vessels and diminish the chance of cardiovascular occasions such as heart assault or stroke.

Supports Cardiovascular Health: Nattokinase's capacity to advance fibrinolysis and move forward blood stream contributes to generally cardiovascular wellbeing. It may offer assistance lower blood weight, diminish the chance of blood clots, and progress lipid profiles by bringing down LDL cholesterol and triglyceride levels whereas expanding HDL cholesterol levels.

Reduces Inflammation and Oxidative Stress: Some research suggests that nattokinase may have anti-inflammatory and antioxidant properties, which can help reduce inflammation and oxidative stress in blood vessels and tissues. This may contribute to improved endothelial function and overall cardiovascular health.

Supports Healthy Blood Viscosity: Nattokinase helps to maintain healthy blood viscosity, which refers to the thickness or stickiness of blood. By promoting fibrinolysis and reducing the formation of blood clots, nattokinase helps to keep blood flowing smoothly and prevent excessive clotting.

May Have Digestive Benefits: While most research on nattokinase has focused on its cardiovascular effects, some studies suggest that it may have potential benefits for digestive health as well. It may help promote gut microbiota balance and support healthy digestion, although more research is needed in this area.

Does Nattokinase lower blood pressure?

One of the potential benefits of Nattokinase is its ability to lower blood pressure. Nattokinase is an enzyme derived from fermented soybeans and has been used in traditional Japanese medicine for centuries. Studies have shown that it may help in reducing high blood pressure by promoting the production of a natural substance called nitric oxide, which helps to relax and widen blood vessels. However, individuals with low blood pressure should exercise caution and consult with a healthcare professional before taking Nattokinase to avoid any undesirable effects.

Animal Studies: Several animal studies have shown that nattokinase supplementation may lead to reductions in blood pressure. For example, a study published in the Journal of Hypertension Research found that nattokinase supplementation significantly lowered blood pressure in spontaneously hypertensive rats compared to a control group.

Human Studies: While there is limited research on nattokinase's effects on blood pressure in humans, some small-scale studies and clinical trials have suggested potential benefits. For instance, a study published in the journal Hypertension Research found that nattokinase supplementation led to modest reductions in blood pressure in individuals with prehypertension or hypertension.

Mechanism of Action: The exact mechanism by which nattokinase may lower blood pressure is not fully understood. However, it is believed that its fibrinolytic activity, which helps break down fibrin and improve blood flow, may play a role. By promoting fibrinolysis and reducing blood viscosity, nattokinase may enhance circulation and reduce the resistance to blood flow, leading to lower blood pressure.

Combined Effects: Some studies have investigated the combined effects of nattokinase with other compounds, such as vitamin K2 or garlic extract, on blood pressure. These studies have reported additional benefits in blood pressure reduction, suggesting that nattokinase may have synergistic effects when combined with other cardiovascular-supportive nutrients.

While these findings are promising, it's important to note that more research is needed to fully understand the effects of nattokinase on blood pressure and to determine optimal dosages and treatment protocols. Additionally, individual responses to nattokinase supplementation may vary, and its effects may be influenced by factors such as diet, lifestyle, and overall health status. As always, it's advisable to consult with a healthcare professional before starting any new supplement regimen, especially if you have hypertension or are taking medications for blood pressure management.

Does Nattokinase thin the blood?

Another important role of Nattokinase is its potential to thin the blood. It acts as a natural blood-thinning agent by breaking down fibrin, a protein involved in blood clotting. By reducing the formation of blood clots, Nattokinase may help improve blood flow and prevent the risk of cardiovascular diseases such as heart attacks and strokes. However, individuals taking blood-thinning medications or those with bleeding disorders should seek medical advice before using Nattokinase to avoid any potential interactions or complications.

What to avoid when taking Nattokinase?

When taking Nattokinase, there are certain things to be mindful of. Firstly, it is important to avoid consuming alcohol excessively, as alcohol can potentially interfere with the effectiveness of Nattokinase. Additionally, individuals with bleeding disorders, ulcers, or undergoing surgery should avoid using Nattokinase without consulting their healthcare provider, as it may increase the risk of bleeding. It is always recommended to inform your healthcare professional about any ongoing medications or conditions before starting Nattokinase supplementation.

Overall, nattokinase plays a crucial role in promoting cardiovascular health by breaking down fibrin and improving blood flow and circulation. While more research is needed to fully understand its mechanisms and potential benefits, nattokinase remains an interesting area of study in the field of cardiovascular and functional medicine.

If you are interested in Nattokinase or have any further questions, please feel free to contact us at sales@pioneerbiotech.com. Our team at Pioneer specializes in providing professional-grade natural health products and supplements.


1. Kim, J. Y., Gum, S. N., Paik, J. K., Lim, H. H., Kim, K. C., Ogasawara, K., Inoue, K., Jang, Y., & Lee, J. H. (2015). Effects of nattokinase on blood pressure: A randomized, controlled trial. Hypertension research, 38(12), 849–852. [Link]

2. Moghissi, K., Lea, G., & Mathers, C. (2005). Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. The Journal of Alternative and Complementary Medicine, 11(2), 379–381. [Link]

3. Kolaczkowska, E., & Kubes, P. (2013). Neutrophil recruitment and function in health and inflammation. Nature reviews. Immunology, 13(3), 159–175. [Link

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