natural nattokinase
HACCP ISO22002 Certified
EU USDA Organic Certified
Kosher Halal Certified
Prompt and Secure Shipment
Ready Stock in Local Warehouse
Prompt and Secure Shipment
Plant Audition Accepted
Gift Sample Available
Paperwork Supported
- Product Description
Premium Natural Nattokinase - Leading Manufacturer & Supplier | Pioneer Biotech
Your trusted source for premium natural nattokinase since 2012. As a professional manufacturer headquartered in Xi'an, China, we specialize in delivering high-purity nattokinase extracted from traditional Japanese fermented soybeans through advanced biotechnology. Our product stands out with superior fibrinolytic activity (measured in FU), guaranteed enzymatic integrity, and complete compliance with international quality standards including HACCP, ISO22002, and organic certifications. Unlike synthetic alternatives, our product maintains exceptional biological activity while being non-GMO and free from harmful additives. With ready stock in local warehouses, 24-hour customer support, and flexible OEM/ODM services, we make sourcing reliable nattokinase simple and secure for your business.
What is Natural Nattokinase?
The item is a strong fibrinolytic protein classified as a serine protease. It's extracted from natto, a conventional Japanese aged soybean nourishment that has been expended for thousands of years.
The generation prepare includes maturing non-GMO soybeans with Bacillus subtilis natto microbes. This aging enacts the protein, making a effective compound with momentous organic activity.
What makes this chemical uncommon? It straightforwardly debases fibrin in blood clots. It moreover upgrades your body's characteristic generation of plasmin and urokinase—both fundamental clot-dissolving agents.
You'll discover this chemical measured in Fibrinolytic Units (FU). Higher FU values show more noteworthy enzymatic movement and effectiveness.
The Japanese population's longer life expectancies and lower cardiovascular infection rates are frequently connected to normal natto utilization. Inquire about appears that diets wealthy in natto connect with diminished heart infection mortality rates.
Today, whereas you can still appreciate natto as a nourishment, the item is accessible as a filtered supplement. This makes it open around the world without the obtained taste of conventional matured soybeans.

Why Choose Pioneer as Your Natural Nattokinase Supplier?
Service First, Clients Oriented
Your commerce needs unwavering quality. We keep up prepared stock in nearby distribution centers over numerous districts, guaranteeing provoke shipment without delays.
You can ask blessing tests some time recently committing to bulk orders. Our group gives 24-hour online communication bolster to reply your specialized questions instantly.
Internationally Recognized Certifications
We've contributed a long time building a comprehensive quality administration framework. Our office holds different certifications:
- ISO9001 & ISO22000 for quality and food safety management
- HACCP for hazard analysis and critical control points
- EU-ORGANIC and USDA-ORGANIC certifications
- Kosher and Halal certifications for diverse market requirements
- USFDA compliance for U.S. market access
GMP-Standard Production Facility
Our fabricating works beneath GMP workshop measures. This guarantees each clump meets pharmaceutical-grade quality expectations.
Plant reviews are invited. We're sure in our straightforward forms and empower you to confirm our capabilities firsthand.
Complete Printed material Support
International exchange requires documentation. We give all vital certificates, test reports, and administrative printed material to streamline your consequence prepare.
Technical Specifications and COA
Parameter | Specification |
Product Name | Natural Nattokinase Enzyme Powder |
CAS Number | 133876-92-3 |
Source | Fermented Non-GMO Soybeans (Bacillus subtilis natto) |
Activity | 5,000 FU/g to 20,000 FU/g (customizable) |
Appearance | Light yellow to off-white fine powder |
Solubility | Water-soluble |
Moisture | ≤ 5.0% |
Particle Size | 95% through 80 mesh |
Heavy Metals | ≤ 10 ppm |
Lead (Pb) | ≤ 2 ppm |
Arsenic (As) | ≤ 1 ppm |
Total Plate Count | ≤ 1,000 cfu/g |
Yeast & Mold | ≤ 100 cfu/g |
E. Coli | Negative |
Salmonella | Negative |
Vitamin K2 Content | < 2 mcg/g (removed through proprietary filtration) |
Shelf Life | 24 months when stored properly |
Storage Conditions | Store below 25°C, away from moisture and direct light |
Packaging | 1 kg/aluminum foil bag; 25 kg/fiber drum |
Certificate of Analysis (COA) available upon request for each batch.
Core Product Functions
Cardiovascular Support
The essential work is fibrinolysis—breaking down fibrin in blood clots. This makes a difference keep up solid blood stream all through your circulatory system.
It bolsters ordinary blood weight levels by moving forward blood vessel versatility and decreasing vascular resistance.
Enhanced Plasmin Production
Beyond coordinate fibrin corruption, it invigorates your body's characteristic clot-dissolving instruments. This makes a maintained cardiovascular defensive effect.
Respiratory Wellness
Studies illustrate its capacity to lean bodily fluid discharges. This moves forward sinus wellbeing and may advantage those with persistent respiratory conditions.
Metabolic Balance
The probiotic properties determined from the maturation prepare back intestine microbiome wellbeing. A adjusted intestine contributes to progressed digestion system and weight management.
Anti-inflammatory Properties
Research shows potential anti-inflammatory impacts that may back generally systemic wellbeing and cellular function.

Key Product Advantages
Superior Enzymatic Stability
Our extraction handle jam enzymatic judgment indeed beneath challenging conditions. The powder keeps up action through tablet compression and shifted stomach related pH levels.
Non-GMO and Clean Label
Sourced only from non-genetically altered soybeans. No manufactured added substances, fillers, or counterfeit preservatives.
Vitamin K2 Removed
Our restrictive filtration evacuates Vitamin K2. This makes our item secure for people who require to dodge Vitamin K admissions due to medicine interactions.
High Bioavailability
Designed for ideal retention in the little digestive tract. When appropriately defined with enteric coatings, bioavailability surpasses 85%.
Standardized Potency
Every bunch is tried and standardized to your indicated FU movement level. This guarantees reliable execution over generation runs.
Long Rack Life
In powder frame, our item remains steady for 24 months beneath legitimate capacity conditions. This diminishes stock chance and waste.
Diverse Application Fields
Dietary Supplements (B2C Market)
You can define our protein into capsules or tablets. Standard dosing ranges from 2,000 to 4,000 FU per serving for common cardiovascular support.
Popular designs incorporate:
- Vegetarian capsules with enteric coating
- Softgels with oil suspension for enhanced stability
- Sublingual tablets for rapid absorption
Functional Foods (B2B Market)
The powder integrates seamlessly into:
- Fortified beverage mixes
- Nutritional bars and snacks
- Protein powders with cardiovascular benefits
- Probiotic yogurt products
Our enzyme performs exceptionally well in dry-matrix environments where moisture control is critical.
Professional Therapeutic Blends
Health practitioners often combine natural nattokinase with complementary ingredients:
- Red Yeast Rice for comprehensive lipid management
- CoQ10 for cellular energy and heart health
- Omega-3 fatty acids for synergistic cardiovascular support
- Curcumin for enhanced anti-inflammatory effects
- Cosmetic Applications
Rising investigate investigates topical applications for made strides microcirculation in skincare formulations.

Manufacturing and Production Process
Raw Material Selection
We source premium non-GMO soybeans from certified natural ranches. Each bunch experiences thorough testing some time recently processing.
Fermentation
Soybeans are immunized with carefully chosen Bacillus subtilis natto strains. Maturation happens in controlled temperature and mugginess conditions for 18-24 hours.
Enzyme Extraction
Post-fermentation, we utilize exclusive extraction strategies that protect enzymatic movement whereas expelling undesirable compounds like Vitamin K2.
Purification
Multiple filtration and chromatography steps separate the immaculate chemical. This expels remaining proteins, filaments, and microbial byproducts.
Concentration and Drying
The fluid extract experiences low-temperature concentration. Splash drying changes over it to powder whereas keeping up natural activity.
Standardization
The last powder is tried for FU action. We alter concentrations to meet your indicated strength requirements.
Quality Testing
Every group experiences comprehensive testing some time recently discharge. As it were items assembly all details continue to packaging.

Quality Control (QC) and Testing Standards
In-Process Quality Monitoring
We conduct real-time testing at each generation organize. Basic control focuses are checked persistently to guarantee consistency.
Microbiological Testing
All batches are tested for:
- Total aerobic bacterial count
- Yeast and mold contamination
- Pathogenic bacteria (E. Coli, Salmonella)
Overwhelming Metal Analysis
We utilize ICP-MS innovation to distinguish follow overwhelming metals. Our determinations surpass worldwide security standards.
Activity Assurance
Fibrinolytic movement is measured utilizing standardized strategies endorsed by the Japan Natto Kinase Affiliation (JNKA). This guarantees precise FU labeling.
Stability Testing
Accelerated and real-time soundness ponders affirm rack life claims. We give soundness information to back your administrative submissions.
Third-Party Verification
We welcome third-party research facility testing. Autonomous confirmation includes validity to your item claims.
Certifications and Product Patents
Our facility maintains current certifications for:
- ISO 9001: Quality Management System
- ISO 22000: Food Safety Management
- HACCP: Hazard Analysis Critical Control Points
- EU Organic: European organic product certification
- USDA Organic: United States Department of Agriculture organic certification
- Kosher: Certified by recognized rabbinical authorities
- Halal: Certified for Islamic dietary compliance
These certifications illustrate our commitment to universal quality measures and make showcase passage smoother for your products.
Factory, Lab, and R&D Capabilities
Manufacturing Capacity
Our Xi'an office ranges over 10,000 square meters. Yearly generation capacity surpasses 50 metric tons of standardized chemical products.
Advanced Laboratory
We work an in-house explanatory research facility prepared with:
· High-Performance Liquid Chromatography (HPLC)
· Gas Chromatography-Mass Spectrometry (GC-MS)
· Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
· UV-Vis Spectrophotometry
· Microbiological testing suites
Research & Development Team
Our R&D team includes biochemists, food scientists, and formulation specialists. They work on:
- Improving extraction efficiency
- Developing novel delivery systems
- Creating synergistic ingredient combinations
- Solving formulation challenges for clients
Pilot Generation Line
Before full-scale fabricating, we offer pilot clump generation. This permits you to test advertise reaction with negligible investment.

OEM/ODM and Custom Formulation Services
Flexible Fabricating Solutions
Whether you require bulk powder or wrapped up items, we suit different trade models:
Bulk Powder Supply: Buy standardized powder at your favored FU action for your possess embodiment or tableting.
Private Name Fabricating: We deliver wrapped up capsules or tablets beneath your brand. Least arrange amounts begin at 5,000 bottles.
Custom Definition Advancement: Our group defines interesting mixes combining nattokinase with your chosen complementary ingredients.
Packaging Options
Choose from numerous bundling designs:
- Aluminum foil bags (1 kg, 5 kg, 25 kg for bulk)
- HDPE bottles with desiccant (60-120 count for retail)
- Blister packs for pharmacy distribution
- Sachet packaging for single-serve applications
Label and Artwork Design
Our plan group helps with name creation that complies with administrative necessities in your target market.

Company Exhibitions and Global Presence
Pioneer Biotech effectively takes part in major worldwide exchange shows to interface with accomplices around the world. We keep up a worldwide nearness through:
- Distribution Systems: Set up associations in North America, Europe, Southeast Asia, and Australia
- Technical Back Groups: Multilingual client benefit for consistent communication
- Regulatory Mastery: Information of purport necessities over diverse markets
Our commitment to building long-term connections amplifies past exchanges. We see our clients as accomplices in advancing common wellbeing arrangements all inclusive.

Transportation and Packaging
Secure Packaging
Bulk powder arrives in:
- Double-sealed aluminum foil bags for small quantities (1-5 kg)
- Fiber drums with inner polyethylene bags for larger orders (25 kg)
- Desiccant packets included to prevent moisture absorption
Shipping Options
We offer numerous shipping strategies based on your direness and budget:
Express Messenger: DHL, FedEx, or UPS for tests and little orders (3-7 days)
Air Cargo: For medium amounts requiring speedier conveyance (5-10 days)
Sea Cargo: Most prudent for bulk orders (20-45 days depending on destination)
Temperature-Controlled Logistics
While our powder is steady at room temperature, we can orchestrate temperature-controlled shipping for touchy climates or particular client requirements.
Customs Clearance Support
We give all essential documentation:
- Commercial invoice
- Packing list
- Certificate of Analysis
- Health certificates
- Organic certificates (when applicable)
- Country-specific import documents
Our experienced logistics team ensures smooth customs clearance and tracks shipments until delivery confirmation.

FAQ
Q: How is the movement of the item measured?
A: Movement is measured in Fibrinolytic Units (FU) utilizing a standardized fibrin corruption strategy endorsed by the Japan Natto Kinase Affiliation (JNKA). This guarantees exact and reliable strength over batches.
Q: Does your item contain Vitamin K2?
A: Our premium item experiences a restrictive filtration prepare to expel Vitamin K2. Last substance is less than 2 mcg/g, making it secure for those who must dodge Vitamin K intake.
Q: Is the chemical steady at room temperature?
A: Yes, in powder frame, the protein is exceedingly steady at room temperature (underneath 25°C). With appropriate capacity absent from dampness and light, it keeps up action for 24 months.
Q: What is the suggested day by day dosage?
A: For common cardiovascular bolster, the industry standard is 2,000 FU per day. Higher dosages (up to 4,000-6,000 FU) are now and then utilized beneath clinical supervision or for particular wellbeing goals.
Q: Can the protein survive stomach acid?
A: Whereas the chemical is touchy to amazingly moo pH, commercial applications ordinarily utilize enteric-coated capsules or specialized granulation methods. This guarantees the chemical comes to the little digestive tract where it's ingested effectively.
Q: What is your least arrange quantity?
A: For bulk powder, our MOQ is 25 kg. For wrapped up items beneath private name, the MOQ is regularly 5,000 bottles, in spite of the fact that this changes by detailing complexity.
Q: How long does generation take?
A: Standard bulk powder orders transport inside 7-10 commerce days. Custom definition ventures require 15-30 days depending on complexity and testing requirements.
Q: Do you give samples?
A: Yes, we offer blessing tests (50-100g) for quality assessment some time recently you put bulk orders. Tests dispatch inside 2-3 commerce days.
Contact Us for a Technical Quote
Ready to source premium natural nattokinase for your product line? Our team is standing by to discuss your specific requirements.
What We Need to Provide an Accurate Quote:
- Desired FU activity level
- Order quantity (MOQ applies)
- Preferred packaging format
- Destination country
- Any special requirements (organic certification, specific testing, etc.)
Email: sales@pioneerbiotech.com
Our technical sales team typically responds within 2 hours during business hours. We'll provide:
- Detailed product specifications
- Competitive pricing
- Estimated delivery timeline
- Technical data sheets and COA samples
Whether you're defining your to begin with cardiovascular supplement or growing an existing item line, Pioneer Biotech conveys the quality, consistency, and back you require to succeed.










